In 1949, Canadian psychologist Donald O. Hebb published The Organization of Behavior: A Neuropsychological Theory, proposing what became known as Hebbian learning, summarised in the phrase “cells that fire together wire together”, arguing that when one neuron repeatedly and persistently helps fire another, the synaptic connection between them is strengthened, thereby providing a neurophysiological basis for learning and memory; this principle, often formalised in computational terms by researchers such as Frank Rosenblatt (1958) in his work on the perceptron and later mathematically elaborated by Teuvo Kohonen (1982) in self-organizing maps, has profoundly shaped neuroscience, psychology, and artificial intelligence by explaining how experience sculpts the brain through activity-dependent plasticity. From a Christian perspective, Hebb’s insight resonates deeply with the Biblical vision of formative habit and moral transformation: Proverbs 23:7 teaches, “As a man thinketh in his heart, so is he,” while Romans 12:2 calls believers to “be transformed by the renewing of your mind,” suggesting that repeated patterns of thought and action, whether virtuous or sinful, literally and spiritually shape the person, a theme echoed in Christian theology from Augustine of Hippo’s account of disordered loves to Thomas Aquinas’s virtue ethics. Thus, Hebbian learning can be seen as illuminating the embodied means by which God’s design for growth, sanctification, and character formation operates within creation. For personal wellbeing, the principle underscores the power of intentional practice (gratitude, prayer, forgiveness, disciplined study) in strengthening life-giving neural pathways, while warning that repeated anxiety, resentment, or vice can entrench harmful circuits. For societal health, it highlights how communal liturgies, education systems, media exposure, and cultural narratives repeatedly activate shared patterns that become collectively “wired,” shaping social trust, empathy, prejudice, or division, thereby calling individuals and communities alike to cultivate practices that foster truth, love, and justice.